BMRB Entry 51061

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR51061

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Title:
mMLKL
Deposition date:
2021-08-19
Original release date:
2022-03-08
Authors:
Sethi, Ashish; Horne, Chris; Gooley, Paul R.; Murphy, James
Citation:

Citation: Sethi, Ashish; Horne, Christopher; Fitzgibbon, Cheree; Wilde, Karyn; Davies, Katherine; Garnish, Sarah; Jacobsen, Annette; Samson, Andre; Hildebrand, Joanne; Wardak, Ahmad; Czabotar, Peter; Petrie, Emma; Gooley, Paul; Murphy, James. "Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL"  Cell Death Diff. 29, 1804-1815 (2022).
PubMed: 35264780

Assembly members:

Assembly members:
entity_1, polymer, 163 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: E. coli   Taxonomy ID: 562   Superkingdom: Bacteria   Kingdom: not available   Genus/species: Escherichia coli

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pETNusH Htb

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: GAMGSMDKLGQIIKLGQLIY EQCEKMKYCRKQCQRLGNRV HGLLQPLQRLQAQGKKNLPD DITAALGRFDEVLKEANQQI EKFSKKSHIWKFVSVGNDKI LFHEVNEKLRDVWEELLLLL QVYHWNTVSDVSQPASWQQE DRQDAEEDGNENMKVILMQL QIS

Data sets:
Data typeCount
13C chemical shifts244
15N chemical shifts151
1H chemical shifts151

Additional metadata:

  • Assembly
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Assembly:

Entity Assembly IDEntity NameEntity ID
1mMLKL monomer1

Entities:

Entity 1, mMLKL monomer 163 residues - Formula weight is not available

1   GLYALAMETGLYSERMETASPLYSLEUGLY
2   GLNILEILELYSLEUGLYGLNLEUILETYR
3   GLUGLNCYSGLULYSMETLYSTYRCYSARG
4   LYSGLNCYSGLNARGLEUGLYASNARGVAL
5   HISGLYLEULEUGLNPROLEUGLNARGLEU
6   GLNALAGLNGLYLYSLYSASNLEUPROASP
7   ASPILETHRALAALALEUGLYARGPHEASP
8   GLUVALLEULYSGLUALAASNGLNGLNILE
9   GLULYSPHESERLYSLYSSERHISILETRP
10   LYSPHEVALSERVALGLYASNASPLYSILE
11   LEUPHEHISGLUVALASNGLULYSLEUARG
12   ASPVALTRPGLUGLULEULEULEULEULEU
13   GLNVALTYRHISTRPASNTHRVALSERASP
14   VALSERGLNPROALASERTRPGLNGLNGLU
15   ASPARGGLNASPALAGLUGLUASPGLYASN
16   GLUASNMETLYSVALILELEUMETGLNLEU
17   GLNILESER

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