Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR51158
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Citation: Becette, Owen; Tran, Anh; Jones, Jace; Marino, John; Brinson, Robert. "Structural Fingerprinting of Short Interfering RNA Therapeutics by Solution Nuclear Magnetic Resonance Spectroscopy" Nucleic Acid Ther. 32, 267-279 (2022).
PubMed: 35263184
Assembly members:
entity_1, polymer, 17 residues, Formula weight is not available
entity_2, polymer, 17 residues, Formula weight is not available
Natural source: Common Name: not available Taxonomy ID: not available Superkingdom: not available Kingdom: not available Genus/species: not available not available
Experimental source: Production method: chemical synthesis
Entity Sequences (FASTA):
entity_1: GCXXXXXXXXXXXXGTT
entity_2: CGXXXXXXXXXXXXCTT
Data type | Count |
13C chemical shifts | 87 |
15N chemical shifts | 29 |
19F chemical shifts | 15 |
1H chemical shifts | 168 |
Entity Assembly ID | Entity Name | Entity ID |
---|---|---|
1 | Sense siRNA | 1 |
2 | Antisense siRNA | 2 |
Entity 1, Sense siRNA 17 residues - Formula weight is not available
Antisense strand of the modified siRNA
1 | G | C | FA | 5FU | FA | MRG | FC | MRA | FC | 5FU | ||||
2 | FG | 5FU | 5FU | MRC | G | DT | DT |
Entity 2, Antisense siRNA 17 residues - Formula weight is not available
Sense strand of the unmodified siRNA
1 | C | G | MRA | FA | MRC | FA | MRG | FU | MRG | FC | ||||
2 | MRU | FA | MRU | FG | C | DT | DT |