BMRB Entry 51169

Title:
Solution NMR resonance assignment of PD-L1
Deposition date:
2021-11-05
Original release date:
2022-06-08
Authors:
Rizzo, Domenico; Cerofolini, Linda; Giuntini, Stefano; Iozzino, Luisa; Pergola, Carlo; Sacco, Francesca; Palmese, Angelo; Ravera, Enrico; Luchinat, Claudio; Baroni, Fabio; Fragai, Marco
Citation:

Citation: Rizzo, Domenico; Cerofolini, Linda; Giuntini, Stefano; Iozzino, Luisa; Pergola, Carlo; Sacco, Francesca; Palmese, Angelo; Ravera, Enrico; Luchinat, Claudio; Baroni, Fabio; Fragai, Marco. "Epitope Mapping and Binding Assessment by Solid-State NMR Provide a Way for the Development of Biologics under the Quality by Design Paradigm"  J. Am. Chem. Soc. 144, 10006-10016 (2022).
PubMed: 35617699

Assembly members:

Assembly members:
entity_1, polymer, 118 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET-21a (+) plasmid

Data sets:
Data typeCount
13C chemical shifts323
15N chemical shifts111
1H chemical shifts111

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1PD-L11

Entities:

Entity 1, PD-L1 118 residues - Formula weight is not available

1   METALAPHETHRVALTHRVALPROLYSASP
2   LEUTYRVALVALGLUTYRGLYSERASNMET
3   THRILEGLUCYSLYSPHEPROVALGLULYS
4   GLNLEUASPLEUALAALALEUILEVALTYR
5   TRPGLUMETGLUASPLYSASNILEILEGLN
6   PHEVALHISGLYGLUGLUASPLEULYSVAL
7   GLNHISSERSERTYRARGGLNARGALAARG
8   LEULEULYSASPGLNLEUSERLEUGLYASN
9   ALAALALEUGLNILETHRASPVALLYSLEU
10   GLNASPALAGLYVALTYRARGCYSMETILE
11   SERTYRGLYGLYALAASPTYRLYSARGILE
12   THRVALLYSVALASNALAPROTYR

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