BMRB Entry 51179

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR51179

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Title:
Alpha X I domain NMR backbone assignment
Deposition date:
2021-11-16
Original release date:
2021-12-16
Authors:
Abousaway, Omar; Mazhar, Zahra; Aboagye, Collins; Sen, Mehmet
Citation:

Citation: Manandhar, Pragya; Abousaway, Omar; Mazhar, Zahra; Moussa, Zeinab; Aboagye, Collins; Lim, Daniel; Yu, Tannon; Byrnes, James; Briggs, James; Sen, Mehmet. "Heterotropic roles of divalent cations in the establishment of allostery and affinity maturation of integrin aXb2"  Cell Rep. 40, 111254-111254 (2022).
PubMed: 36001965

Assembly members:

Assembly members:
entity_1, polymer, 189 residues, 21343.25 Da.
entity_MG, non-polymer, 24.305 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pet28a

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: QDIVFLIDGSGSISSRNFAT MMNFVRAVISQFQRPSTQFS LMQFSNKFQTHFTFEEFRRS SNPLSLLASVHQLQGFTYTA TAIQNVVHRLFHASYGARRD ATKILIVITDGKKEGDSLDY KDVIPMADAAGIIRYAIGVG LAFQNRNSWKELNDIASKPS QEHIFKVEDFDALKDIQNQL KEKIFAIEG

Data sets:
Data typeCount
13C chemical shifts514
15N chemical shifts167
1H chemical shifts167

Additional metadata:

  • Assembly
  • Samples and Experiments
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  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1human alpha X integrin1
2Mg2+ ion2

Entities:

Entity 1, human alpha X integrin 189 residues - 21343.25 Da.

1   GLNASPILEVALPHELEUILEASPGLYSER
2   GLYSERILESERSERARGASNPHEALATHR
3   METMETASNPHEVALARGALAVALILESER
4   GLNPHEGLNARGPROSERTHRGLNPHESER
5   LEUMETGLNPHESERASNLYSPHEGLNTHR
6   HISPHETHRPHEGLUGLUPHEARGARGSER
7   SERASNPROLEUSERLEULEUALASERVAL
8   HISGLNLEUGLNGLYPHETHRTYRTHRALA
9   THRALAILEGLNASNVALVALHISARGLEU
10   PHEHISALASERTYRGLYALAARGARGASP
11   ALATHRLYSILELEUILEVALILETHRASP
12   GLYLYSLYSGLUGLYASPSERLEUASPTYR
13   LYSASPVALILEPROMETALAASPALAALA
14   GLYILEILEARGTYRALAILEGLYVALGLY
15   LEUALAPHEGLNASNARGASNSERTRPLYS
16   GLULEUASNASPILEALASERLYSPROSER
17   GLNGLUHISILEPHELYSVALGLUASPPHE
18   ASPALALEULYSASPILEGLNASNGLNLEU
19   LYSGLULYSILEPHEALAILEGLUGLY

Entity 2, Mg2+ ion - Mg - 24.305 Da.

1   MG

Related Database Links:

NCBI 3687

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks