BMRB Entry 51283

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR51283

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Title:
Backbone 1H, 13C, and 15N Chemical Shift Assignments for vRAGE(23-125)
Deposition date:
2022-01-18
Original release date:
2022-10-19
Authors:
Long, Houfang; zhang, shengnan; Zeng, Shuyi; Liu, Cong; Li, Dan
Citation:

Citation: Long, Houfang; Zhang, Shengnan; Zeng, Shuyi; Tong, Yilun; Liu, Jun; Liu, Cong; Li, Dan. "Interaction of RAGE with a-synuclein fibrils mediates inflammatory response of microglia"  Cell Rep. 40, 111401-111401 (2022).
PubMed: 36130498

Assembly members:

Assembly members:
entity_1, polymer, 104 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET-28a

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: GAQNITARIGEPLVLKCKGA PKKPPQRLEWKLNTGRTEAW KVLSPQGGGPWDSVARVLPN GSLFLPAVGIQDEGIFRCQA MNRNGKETKSNYRVRVYQIP GKPE

Data sets:
Data typeCount
13C chemical shifts166
15N chemical shifts73
1H chemical shifts73

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1vRAGE1

Entities:

Entity 1, vRAGE 104 residues - Formula weight is not available

The construct was made for the residues 23-125 of human RAGE, and refereed as vRAGE.

1   GLYALAGLNASNILETHRALAARGILEGLY
2   GLUPROLEUVALLEULYSCYSLYSGLYALA
3   PROLYSLYSPROPROGLNARGLEUGLUTRP
4   LYSLEUASNTHRGLYARGTHRGLUALATRP
5   LYSVALLEUSERPROGLNGLYGLYGLYPRO
6   TRPASPSERVALALAARGVALLEUPROASN
7   GLYSERLEUPHELEUPROALAVALGLYILE
8   GLNASPGLUGLYILEPHEARGCYSGLNALA
9   METASNARGASNGLYLYSGLUTHRLYSSER
10   ASNTYRARGVALARGVALTYRGLNILEPRO
11   GLYLYSPROGLU

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks