BMRB Entry 51492

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR51492

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Title:
NTD TDP-43 with 3% SB3-10
Deposition date:
2022-06-14
Original release date:
2022-08-08
Authors:
Cantarutti, Cristina; Moretti, Matteo; Corazza, Alessandra; Chiti, Fabrizio
Citation:

Citation: Moretti, Matteo; Marzi, Isabella; Cantarutti, Cristina; Vivoli Vega, Mirella; Mandaliti, Walter; Mimmi, Maria Chiara; Bemporad, Francesco; Corazza, Alessandra; Chiti, Fabrizio. "Conversion of the Native N-Terminal Domain of TDP-43 into a Monomeric Alternative Fold with Lower Aggregation Propensity"  Molecules 27, 4309-4309 (2022).
PubMed: 35807552

Assembly members:

Assembly members:
entity_1, polymer, 77 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: E. coli   Taxonomy ID: 562   Superkingdom: Bacteria   Kingdom: not available   Genus/species: Escherichia coli

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pNIC28-Bsa4

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: MSEYIRVTEDENDEPIEIPS EDDGTVLLSTVTAQFPGACG LRYRNPVSQCMRGVRLVEGI LHAPDAGWGNLVYVVNY

Data sets:
Data typeCount
13C chemical shifts390
15N chemical shifts129
1H chemical shifts129

Additional metadata:

  • Assembly
  • Samples and Experiments
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Assembly:

Entity Assembly IDEntity NameEntity ID
1TDP-43, form A1
2TDP-43, form B1

Entities:

Entity 1, TDP-43, form A 77 residues - Formula weight is not available

1   METSERGLUTYRILEARGVALTHRGLUASP
2   GLUASNASPGLUPROILEGLUILEPROSER
3   GLUASPASPGLYTHRVALLEULEUSERTHR
4   VALTHRALAGLNPHEPROGLYALACYSGLY
5   LEUARGTYRARGASNPROVALSERGLNCYS
6   METARGGLYVALARGLEUVALGLUGLYILE
7   LEUHISALAPROASPALAGLYTRPGLYASN
8   LEUVALTYRVALVALASNTYR

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