BMRB Entry 51494

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR51494

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Title:
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 low complexity domain with methionine sulfoxide modifications
Deposition date:
2022-06-16
Original release date:
2023-01-30
Authors:
Carrasco, Jaime; Anton, Rosa; Pantoja-Uceda, David; Laurents, Douglas; Oroz, Javier
Citation:

Citation: Carrasco, Jaime; Anton, Rosa; Valbuena, Alejandro; Pantoja-Uceda, David; Mukhi, Mayur; Hervas, Ruben; Laurents, Douglas; Gasset, Maria; Oroz, Javier. "Metamorphism in TDP-43 prion-like domain determines chaperone recognition"  Nat. Commun. 14, 466-466 (2023).
PubMed: 36709343

Assembly members:

Assembly members:
entity_1, polymer, 141 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET28a

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: GRFGGNPGGFGNQGGFGNSR GGGAGLGNNQGSNXGGGXNF GAFSINPAXXAAAQAALQSS WGXXGXLASQQNQSGPSGNN QNQGNXQREPNQAFGSGNNS YSGSNSGAAIGWGSASNAGS GSGFNGGFGSSXDSKSSGWG X

Data sets:
Data typeCount
13C chemical shifts351
15N chemical shifts136
1H chemical shifts457

Additional metadata:

  • Assembly
  • Samples and Experiments
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Assembly:

Entity Assembly IDEntity NameEntity ID
1TDP-43 PLD1

Entities:

Entity 1, TDP-43 PLD 141 residues - Formula weight is not available

1   GLYARGPHEGLYGLYASNPROGLYGLYPHE
2   GLYASNGLNGLYGLYPHEGLYASNSERARG
3   GLYGLYGLYALAGLYLEUGLYASNASNGLN
4   GLYSERASNMHOGLYGLYGLYMHOASNPHE
5   GLYALAPHESERILEASNPROALAMHOMHO
6   ALAALAALAGLNALAALALEUGLNSERSER
7   TRPGLYMHOMHOGLYMHOLEUALASERGLN
8   GLNASNGLNSERGLYPROSERGLYASNASN
9   GLNASNGLNGLYASNMHOGLNARGGLUPRO
10   ASNGLNALAPHEGLYSERGLYASNASNSER
11   TYRSERGLYSERASNSERGLYALAALAILE
12   GLYTRPGLYSERALASERASNALAGLYSER
13   GLYSERGLYPHEASNGLYGLYPHEGLYSER
14   SERMHOASPSERLYSSERSERGLYTRPGLY
15   MHO

Related Database Links:

UNP Q13148
AlphaFold Q96DJ0

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks