BMRB Entry 51672

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR51672

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Title:
GRASP peptide
Deposition date:
2022-10-25
Original release date:
2023-07-03
Authors:
Borner, Tito; Tinsley, Ian; Milliken, Brandon; Najjar, Nicholas; Kerwood, Deborah; De Jonghe, Bart; Doyle, Robert; Hayes, Matthew
Citation:

Citation: Borner, Tito; Tinsley, Ian; Milliken, Brandon; Doebley, Sarah; Najjar, Nicholas; Kerwood, Deborah; De Jonghe, Bart; Hayes, Matthew; Doyle, Robert. "Creation of a Peptide Antagonist of the GFRAL-RET Receptor Complex for the Treatment of GDF15-Induced Malaise"  J. Med. Chem. 66, 11237-11249 (2023).
PubMed: 37506293

Assembly members:

Assembly members:
entity_1, polymer, 29 residues, 3280 Da.

Natural source:

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: TKEELIHAHADPMVLIQKTD TGVSLQTYD

Data sets:
Data typeCount
13C chemical shifts75
1H chemical shifts175

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1PeptideGRASP1

Entities:

Entity 1, PeptideGRASP 29 residues - 3280 Da.

1   THRLYSGLUGLULEUILEHISALAHISALA
2   ASPPROMETVALLEUILEGLNLYSTHRASP
3   THRGLYVALSERLEUGLNTHRTYRASP