BMRB Entry 51835

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR51835

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Title:
Binding of Rho GDP-dissociation inhibitor to its GTPase clients relies on preformed secondary structural properties of the binding interface
Deposition date:
2023-02-16
Original release date:
2024-06-27
Authors:
Medina-Gomez, Sara; Visco, Ilaria; Merino, Felipe; Bieling, Peter; Linser, Rasmus
Citation:

Citation: Medina-Gomez, Sara; Visco, Ilaria; Merino, Felipe; Bieling, Peter; Linser, Rasmus. "Transient Structural Properties of the Rho GDP-Dissociation Inhibitor"  Angew. Chem. Int. Ed. Engl. 63, e202403941-e202403941 (2024).
PubMed: 38853146

Assembly members:

Assembly members:
entity_1, polymer, 208 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: cow   Taxonomy ID: 9913   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Bos taurus

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pGEX6P

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: GPLGMAEQEPTAEQLAQIAA ENEEDEHSVNYKPPAQKSIQ EIQELDKDDESLRKYKEALL GRVAVSADPNVPNVVVTRLT LVSSTAPGPLELDLTGDLES FKKQSFVLKEGVEYRIKISF RVNREIVSGMKYIQHTYRKG VKIDKTDYMVGSYGPRAEEY EFLTPMEEAPKGMLARGSYN IKSRFTDDDRTDHLSWEWNL TIKKEWKD

Data sets:
Data typeCount
13C chemical shifts505
15N chemical shifts156
1H chemical shifts156

Additional metadata:

  • Assembly
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Assembly:

Entity Assembly IDEntity NameEntity ID
1RhoGDI1

Entities:

Entity 1, RhoGDI 208 residues - Formula weight is not available

1   GLYPROLEUGLYMETALAGLUGLNGLUPRO
2   THRALAGLUGLNLEUALAGLNILEALAALA
3   GLUASNGLUGLUASPGLUHISSERVALASN
4   TYRLYSPROPROALAGLNLYSSERILEGLN
5   GLUILEGLNGLULEUASPLYSASPASPGLU
6   SERLEUARGLYSTYRLYSGLUALALEULEU
7   GLYARGVALALAVALSERALAASPPROASN
8   VALPROASNVALVALVALTHRARGLEUTHR
9   LEUVALSERSERTHRALAPROGLYPROLEU
10   GLULEUASPLEUTHRGLYASPLEUGLUSER
11   PHELYSLYSGLNSERPHEVALLEULYSGLU
12   GLYVALGLUTYRARGILELYSILESERPHE
13   ARGVALASNARGGLUILEVALSERGLYMET
14   LYSTYRILEGLNHISTHRTYRARGLYSGLY
15   VALLYSILEASPLYSTHRASPTYRMETVAL
16   GLYSERTYRGLYPROARGALAGLUGLUTYR
17   GLUPHELEUTHRPROMETGLUGLUALAPRO
18   LYSGLYMETLEUALAARGGLYSERTYRASN
19   ILELYSSERARGPHETHRASPASPASPARG
20   THRASPHISLEUSERTRPGLUTRPASNLEU
21   THRILELYSLYSGLUTRPLYSASP

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