BMRB Entry 52274
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR52274
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NMR-STAR v3 text file.
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Citation: Sarker, Muzaddid; Aubin, Yves. "Backbone and methyl side-chain resonance assignments of the Fab fragment of adalimumab" Biomol. NMR Assign. 18, 187-192 (2024).
PubMed: 38926254
Assembly members:
entity_1, polymer, 214 residues, Formula weight is not available
entity_2, polymer, 228 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET15b10
Entity Sequences (FASTA):
entity_1: DIQMTQSPSSLSASVGDRVT
ITCRASQGIRNYLAWYQQKP
GKAPKLLIYAASTLQSGVPS
RFSGSGSGTDFTLTISSLQP
EDVATYYCQRYNRAPYTFGQ
GTKVEIKRTVAAPSVFIFPP
SDEQLKSGTASVVCLLNNFY
PREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLT
LSKADYEKHKVYACEVTHQG
LSSPVTKSFNRGEC
entity_2: EVQLVESGGGLVQPGRSLRL
SCAASGFTFDDYAMHWVRQA
PGKGLEWVSAITWNSGHIDY
ADSVEGRFTISRDNAKNSLY
LQMNSLRAEDTAVYYCAKVS
YLSTASSLDYWGQGTLVTVS
SASTKGPSVFPLAPSSKSTS
GGTAALGCLVKDYFPEPVTV
SWNSGALTSGVHTFPAVLQS
SGLYSLSSVVTVPSSSLGTQ
TYICNVNHKPSNTKVDKKVE
PKSCDKTH
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 1321 |
| 15N chemical shifts | 381 |
| 1H chemical shifts | 774 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | Light Chain | 1 |
| 2 | Heavy Chain | 2 |
Entities:
Entity 1, Light Chain 214 residues - Formula weight is not available
| 1 | ASP | ILE | GLN | MET | THR | GLN | SER | PRO | SER | SER | ||||
| 2 | LEU | SER | ALA | SER | VAL | GLY | ASP | ARG | VAL | THR | ||||
| 3 | ILE | THR | CYS | ARG | ALA | SER | GLN | GLY | ILE | ARG | ||||
| 4 | ASN | TYR | LEU | ALA | TRP | TYR | GLN | GLN | LYS | PRO | ||||
| 5 | GLY | LYS | ALA | PRO | LYS | LEU | LEU | ILE | TYR | ALA | ||||
| 6 | ALA | SER | THR | LEU | GLN | SER | GLY | VAL | PRO | SER | ||||
| 7 | ARG | PHE | SER | GLY | SER | GLY | SER | GLY | THR | ASP | ||||
| 8 | PHE | THR | LEU | THR | ILE | SER | SER | LEU | GLN | PRO | ||||
| 9 | GLU | ASP | VAL | ALA | THR | TYR | TYR | CYS | GLN | ARG | ||||
| 10 | TYR | ASN | ARG | ALA | PRO | TYR | THR | PHE | GLY | GLN | ||||
| 11 | GLY | THR | LYS | VAL | GLU | ILE | LYS | ARG | THR | VAL | ||||
| 12 | ALA | ALA | PRO | SER | VAL | PHE | ILE | PHE | PRO | PRO | ||||
| 13 | SER | ASP | GLU | GLN | LEU | LYS | SER | GLY | THR | ALA | ||||
| 14 | SER | VAL | VAL | CYS | LEU | LEU | ASN | ASN | PHE | TYR | ||||
| 15 | PRO | ARG | GLU | ALA | LYS | VAL | GLN | TRP | LYS | VAL | ||||
| 16 | ASP | ASN | ALA | LEU | GLN | SER | GLY | ASN | SER | GLN | ||||
| 17 | GLU | SER | VAL | THR | GLU | GLN | ASP | SER | LYS | ASP | ||||
| 18 | SER | THR | TYR | SER | LEU | SER | SER | THR | LEU | THR | ||||
| 19 | LEU | SER | LYS | ALA | ASP | TYR | GLU | LYS | HIS | LYS | ||||
| 20 | VAL | TYR | ALA | CYS | GLU | VAL | THR | HIS | GLN | GLY | ||||
| 21 | LEU | SER | SER | PRO | VAL | THR | LYS | SER | PHE | ASN | ||||
| 22 | ARG | GLY | GLU | CYS |
Entity 2, Heavy Chain 228 residues - Formula weight is not available
| 1 | GLU | VAL | GLN | LEU | VAL | GLU | SER | GLY | GLY | GLY | ||||
| 2 | LEU | VAL | GLN | PRO | GLY | ARG | SER | LEU | ARG | LEU | ||||
| 3 | SER | CYS | ALA | ALA | SER | GLY | PHE | THR | PHE | ASP | ||||
| 4 | ASP | TYR | ALA | MET | HIS | TRP | VAL | ARG | GLN | ALA | ||||
| 5 | PRO | GLY | LYS | GLY | LEU | GLU | TRP | VAL | SER | ALA | ||||
| 6 | ILE | THR | TRP | ASN | SER | GLY | HIS | ILE | ASP | TYR | ||||
| 7 | ALA | ASP | SER | VAL | GLU | GLY | ARG | PHE | THR | ILE | ||||
| 8 | SER | ARG | ASP | ASN | ALA | LYS | ASN | SER | LEU | TYR | ||||
| 9 | LEU | GLN | MET | ASN | SER | LEU | ARG | ALA | GLU | ASP | ||||
| 10 | THR | ALA | VAL | TYR | TYR | CYS | ALA | LYS | VAL | SER | ||||
| 11 | TYR | LEU | SER | THR | ALA | SER | SER | LEU | ASP | TYR | ||||
| 12 | TRP | GLY | GLN | GLY | THR | LEU | VAL | THR | VAL | SER | ||||
| 13 | SER | ALA | SER | THR | LYS | GLY | PRO | SER | VAL | PHE | ||||
| 14 | PRO | LEU | ALA | PRO | SER | SER | LYS | SER | THR | SER | ||||
| 15 | GLY | GLY | THR | ALA | ALA | LEU | GLY | CYS | LEU | VAL | ||||
| 16 | LYS | ASP | TYR | PHE | PRO | GLU | PRO | VAL | THR | VAL | ||||
| 17 | SER | TRP | ASN | SER | GLY | ALA | LEU | THR | SER | GLY | ||||
| 18 | VAL | HIS | THR | PHE | PRO | ALA | VAL | LEU | GLN | SER | ||||
| 19 | SER | GLY | LEU | TYR | SER | LEU | SER | SER | VAL | VAL | ||||
| 20 | THR | VAL | PRO | SER | SER | SER | LEU | GLY | THR | GLN | ||||
| 21 | THR | TYR | ILE | CYS | ASN | VAL | ASN | HIS | LYS | PRO | ||||
| 22 | SER | ASN | THR | LYS | VAL | ASP | LYS | LYS | VAL | GLU | ||||
| 23 | PRO | LYS | SER | CYS | ASP | LYS | THR | HIS |
Download HSQC peak lists in one of the following formats:
CSV: Backbone
or all simulated peaks
SPARKY: Backbone
or all simulated peaks