BMRB Entry 52412
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR52412
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NMR-STAR v3 text file.
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Citation: Tateno, Keita; Ando, Takami; Tabata, Maako; Sugasawa, Haruka; Hayashi, Toshifumi; Yu, Sangya; Pm, Sayeesh; Inomata, Kohsuke; Mikawa, Tsutomu; Ito, Yutaka; Ikeya, Teppei. "Different molecular recognition by three domains of the full-length GRB2 to SOS1 proline-rich motifs and EGFR phosphorylated sites" Chem. Sci. 15, 15858-15872 (2024).
PubMed: 39282643
Assembly members:
entity_1, polymer, 217 residues, Formula weight is not available
entity_2, polymer, 10 residues, Formula weight is not available
entity_3, polymer, 7 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET14b
Entity Sequences (FASTA):
entity_1: MEAIAKYDFKATADDELSFK
RGDILKVLNEESDQNWYKAE
LNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHD
GAFLIRESESAPGDFSLSVK
FGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSV
SRNQQIFLRDIEQVPQQPTY
VQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGAAHG
QTGMFPRNYVTPVNRNV
entity_2: VPPPVPPRRR
entity_3: EXINSQV
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 684 |
| 15N chemical shifts | 190 |
| 1H chemical shifts | 790 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | GRB2 | 1 |
| 2 | SOS1 PRM | 2 |
| 3 | EGFR peptide | 3 |
Entities:
Entity 1, GRB2 217 residues - Formula weight is not available
| 1 | MET | GLU | ALA | ILE | ALA | LYS | TYR | ASP | PHE | LYS | ||||
| 2 | ALA | THR | ALA | ASP | ASP | GLU | LEU | SER | PHE | LYS | ||||
| 3 | ARG | GLY | ASP | ILE | LEU | LYS | VAL | LEU | ASN | GLU | ||||
| 4 | GLU | SER | ASP | GLN | ASN | TRP | TYR | LYS | ALA | GLU | ||||
| 5 | LEU | ASN | GLY | LYS | ASP | GLY | PHE | ILE | PRO | LYS | ||||
| 6 | ASN | TYR | ILE | GLU | MET | LYS | PRO | HIS | PRO | TRP | ||||
| 7 | PHE | PHE | GLY | LYS | ILE | PRO | ARG | ALA | LYS | ALA | ||||
| 8 | GLU | GLU | MET | LEU | SER | LYS | GLN | ARG | HIS | ASP | ||||
| 9 | GLY | ALA | PHE | LEU | ILE | ARG | GLU | SER | GLU | SER | ||||
| 10 | ALA | PRO | GLY | ASP | PHE | SER | LEU | SER | VAL | LYS | ||||
| 11 | PHE | GLY | ASN | ASP | VAL | GLN | HIS | PHE | LYS | VAL | ||||
| 12 | LEU | ARG | ASP | GLY | ALA | GLY | LYS | TYR | PHE | LEU | ||||
| 13 | TRP | VAL | VAL | LYS | PHE | ASN | SER | LEU | ASN | GLU | ||||
| 14 | LEU | VAL | ASP | TYR | HIS | ARG | SER | THR | SER | VAL | ||||
| 15 | SER | ARG | ASN | GLN | GLN | ILE | PHE | LEU | ARG | ASP | ||||
| 16 | ILE | GLU | GLN | VAL | PRO | GLN | GLN | PRO | THR | TYR | ||||
| 17 | VAL | GLN | ALA | LEU | PHE | ASP | PHE | ASP | PRO | GLN | ||||
| 18 | GLU | ASP | GLY | GLU | LEU | GLY | PHE | ARG | ARG | GLY | ||||
| 19 | ASP | PHE | ILE | HIS | VAL | MET | ASP | ASN | SER | ASP | ||||
| 20 | PRO | ASN | TRP | TRP | LYS | GLY | ALA | ALA | HIS | GLY | ||||
| 21 | GLN | THR | GLY | MET | PHE | PRO | ARG | ASN | TYR | VAL | ||||
| 22 | THR | PRO | VAL | ASN | ARG | ASN | VAL |
Entity 2, SOS1 PRM 10 residues - Formula weight is not available
| 1 | VAL | PRO | PRO | PRO | VAL | PRO | PRO | ARG | ARG | ARG |
Entity 3, EGFR peptide 7 residues - Formula weight is not available
| 1 | GLU | PTR | ILE | ASN | SER | GLN | VAL |
Download HSQC peak lists in one of the following formats:
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