BMRB Entry 16497

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PDB ID: 2k9j
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR16497
MolProbity Validation Chart

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Title:
1H, 13C, and 15N Chemical Shift Assignments for the Integrin AlphaIIb-Beta3 Transmembrane Complex
Deposition date:
2009-09-15
Original release date:
2009-09-24
Authors:
Lau, Tong-Lay; Ulmer, Tobias
Citation:

Citation: Lau, Tong-Lay; Kim, Chungho; Ginsberg, Mark; Ulmer, Tobias. "The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling"  EMBO J. 28, 1351-1361 (2009).
PubMed: 19279667

Assembly members:

Assembly members:
Integrin_aIIb_transmembrane_segment,_b3_complexed, polymer, 42 residues, Formula weight is not available
Integrin_b3_transmembrane_segment,_aIIb_complexed, polymer, 43 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET-44

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Integrin_aIIb_transmembrane_segment,_b3_complexed: GALEERAIPIWWVLVGVLGG LLLLTILVLAMWKVGFFKRN RP
Integrin_b3_transmembrane_segment,_aIIb_complexed: PESPKGPDILVVLLSVMGAI LLIGLAALLIWKLLITIHDR KEF

Data sets:
Data typeCount
13C chemical shifts203
15N chemical shifts71
1H chemical shifts462

Additional metadata:

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  • Samples and Experiments
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  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1Integrin aIIb transmembrane segment1
2Integrin b3 transmembrane segment2

Entities:

Entity 1, Integrin aIIb transmembrane segment 42 residues - Formula weight is not available

1   GLYALALEUGLUGLUARGALAILEPROILE
2   TRPTRPVALLEUVALGLYVALLEUGLYGLY
3   LEULEULEULEUTHRILELEUVALLEUALA
4   METTRPLYSVALGLYPHEPHELYSARGASN
5   ARGPRO

Entity 2, Integrin b3 transmembrane segment 43 residues - Formula weight is not available

1   PROGLUSERPROLYSGLYPROASPILELEU
2   VALVALLEULEUSERVALMETGLYALAILE
3   LEULEUILEGLYLEUALAALALEULEUILE
4   TRPLYSLEULEUILETHRILEHISASPARG
5   LYSGLUPHE

Related Database Links:

BMRB 16496 16496 17185
PDB 2K1A 2K9J 2KNC 2RMZ 2RN0
DBJ BAG37735 BAI46167 BAG62151 BAJ17755
EMBL CAA29987
GB AAA35926 AAA52597 AAA53150 AAA60114 AAA65936 AAA35927 AAA36121 AAA52589 AAA52600 AAA60122
PRF 1403305A
REF NP_000410 XP_001114526 XP_001150497 XP_002827479 XP_003282434 NP_000203 XP_002748172 XP_002834363 XP_003270746 XP_004041501
SP P08514 P53711 P05106
AlphaFold P08514 P53711 P05106

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