Biological Magnetic Resonance Data BankA Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules |
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Entry ID | Data summary | Entry Title | Citation Title | Authors |
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52284 | Chemical Shifts: 1 set |
Efg1 C-PrLD assignments | Structure and interactions of prion-like domains in transcription factor Efg1 phase separation | Nicolas L Fawzi, Szu-Huan Wang, Tongyin Zheng |
52258 | Chemical Shifts: 1 set |
Efg1 N prion-like domain assignments | Structure and interactions of prion-like domains in transcription factor Efg1 phase separation | Nicolas L Fawzi, Szu-Huan Wang, Tongyin Zheng |
52062 | Chemical Shifts: 1 set |
Backbone 1H and 15N Chemical Shift Assignments for the region 310-350 for TDP-43 C-terminal domain engineered variant 5M to A outside CR | A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain | Azamat Rizuan, Jayakrishna Shenoy Krishnashenoy Padmabai, Jeetain Mittal, Jose F Mercado Ortiz, Nicolas L Fawzi, Priyesh Mohanty |
52061 | Chemical Shifts: 1 set |
Backbone 1H and 15N Chemical Shift Assignments for the region 310-350 for TDP-43 C-terminal domain engineered variant 6F to A | A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain | Azamat Rizuan, Jayakrishna Shenoy Krishnashenoy Padmabai, Jeetain Mittal, Jose F Mercado Ortiz, Nicolas L Fawzi, Priyesh Mohanty |
52060 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for the region 310-350 for TDP-43 C-terminal domain engineered variant 5M to A inside CR | A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain | Azamat Rizuan, Jayakrishna Shenoy Krishnashenoy Padmabai, Jeetain Mittal, Jose F Mercado Ortiz, Nicolas L Fawzi, Priyesh Mohanty |
51067 | Chemical Shifts: 1 set |
FUS RGG1 (164-267) | Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads | Abigail M Janke, Anastasia C Murthy, Da Hee H Seo, Jeetain Mittal, Nicolas L Fawzi, Nina Jovic, Theodora Myrto M Perdikari, Wai Shing S Tang |
51069 | Chemical Shifts: 1 set |
FUS RGG3 (453-507) | Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads | Abigail M Janke, Anastasia C Murthy, Da Hee H Seo, Jeetain Mittal, Nicolas L Fawzi, Nina Jovic, Theodora Myrto M Perdikari, Wai Shing S Tang |
51068 | Chemical Shifts: 1 set |
FUS RGG2 (372-422) | Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads | Abigail M Janke, Anastasia C Murthy, Da Hee H Seo, Jeetain Mittal, Nicolas L Fawzi, Nina Jovic, Theodora Myrto M Perdikari, Wai Shing S Tang |
50766 | Chemical Shifts: 2 sets |
Backbone resonance assignments of LINE-1 retrotransposable element ORF1 protein N-terminal region. | Phase separation of the LINE-1 ORF1 protein is mediated by the N-terminus and coiled-coil domain. | Eileen L Murphy, Gerwald Jogl, Grace Y Li, Jocelyn C Newton, John M Sedivy, Mandar T Naik, Nicolas L Fawzi |
50708 | Chemical Shifts: 1 set |
N-terminal acetylated FUS LC (1-163) | N-terminal acetylation modestly enhances phase separation and reduces aggregation of the low-complexity domain of RNA-binding protein fused in sarcoma | Anastasia Murthy, Anna Bock, Frank Shewmaker, Jeetain Mittal, Nicolas Fawzi, Nina Jovic, WaiShing Tang |
50314 | Chemical Shifts: 1 set |
FtsZ CTD (317-383) | An enhancer sequence in the intrinsically disordered region of FtsZ promotes polymer-guided substrate processing by ClpXP protease | Botai Xuan, Carolina M Pena, Catherine Trebino, Christopher J LaBreck, Jodi L Camberg, Kaylee L Mathews, Marissa G Viola, Negar Rahmani, Nicolas L Fawzi, Theodora M Perdikari, XienYu Chua |
50255 | Chemical Shifts: 1 set |
hnRNPA2 1-189 310K | Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid-liquid phase separation and aggregation | Balabhadra Khatiwada, Joshua Amaya, Mandar Naik, Nicolas Fawzi, Scott Watters, Veronica Ryan, Vincenzo Venditti |
50258 | Chemical Shifts: 2 sets |
ch-TOG 1-250 | Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration | Anne Hart, Camillo Saueressig, Gregory Dignon, Jeetain Mittal, Jeremy Lins, Mandar Naik, Nicolas Fawzi, Theodora Perdikari, Veronica Ryan |
50257 | Chemical Shifts: 1 set |
hnRNPA2 1-189 bound to rA2RE11 | Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid-liquid phase separation and aggregation | Balabhadra Khatiwada, Joshua Amaya, Mandar Naik, Nicolas Fawzi, Scott Watters, Veronica Ryan, Vincenzo Vendetti |
50254 | Chemical Shifts: 1 set |
hnRNPA2 1-189 | Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid-liquid phase separation and aggregation | Balabhadra Khatiwada, Joshua Amaya, Mandar Naik, Nicolas Fawzi, Scott Watters, Veronica Ryan, Vincenzo Vendetti |
50189 | Chemical Shifts: 1 set |
hnRNPF prion-like domain 365-415 backbone and Cbeta chemical shifts | Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration | Anne Hart, Camillo Saueressig, Gregory Dignon, Jeetain Mittal, Jeremy Lins, Mandar Naik, Nicolas Fawzi, Theodora Perdikari, Veronica Ryan |
50090 | Chemical Shifts: 1 set |
G335D TDP43_267-414 | TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function | Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala |
27887 | Chemical Shifts: 1 set Heteronuclear NOE Values: 1 set T1 Relaxation Values: 1 set T2 Relaxation Values: 1 set |
Backbone (1H and 15N) Chemical Shift Assignments and Relaxation Parameters for the low complexity domain of FUS in the condensed phase | Molecular interactions underlying liquid-liquid phase separation of the FUS low complexity domain | Anastasia Murthy, Gregory Dignon, Gul Zerze, Jeetain Mittal, Nicolas Fawzi, Sapun Parekh, Yelena Kan |
27790 | Chemical Shifts: 1 set |
G338A TDP-43_267-414 | TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function | Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala |
27789 | Chemical Shifts: 1 set |
G335S TDP-43_267-414 | TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function | Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala |
27788 | Chemical Shifts: 1 set |
G335N TDP-43_267-414 | TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function | Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala |
27751 | Chemical Shifts: 1 set |
G335N TDP-43_267-414 | TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function | Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala |
27750 | Chemical Shifts: 1 set |
G335A TDP-43_267-414 | TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function | Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala |
27649 | Chemical Shifts: 1 set |
hnRNPA2 low complexity domain 266-341 backbone and Cbeta chemical shifts | The SH3 domain of Fyn kinase interacts with and induces liquid-liquid phase separation of the low-complexity domain of hnRNPA2 | Joshua Amaya, Nicolas Fawzi, Veronica Ryan |
27299 | Chemical Shifts: 1 set |
hnRNPA2 P298L low complexity domain 190-341 backbone and Cbeta chemical shifts | Disease mutation, protein interactions, and posttranslational modifications modulate hnRNPA2 liquid-liquid phase separation | Alexander E Conicella, Charlene V Chabata, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Joshua Amaya, Kathleen A Burke, Nicolas L Fawzi, Rute Silva, Veronica H Ryan |
30345 | Chemical Shifts: 2 sets |
Solution structure of TDP-43 N-terminal domain dimer. | A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation and RNA splicing | Ailin Wang, Alexander E Conicella, Amanda Nourse, Ashley N Reeb, Daniel Ramirez Montero, Erik W Martin, Frank Shewmaker, Hermann Broder B Schmidt, Mandar T Naik, Nicolas L Fawzi, Rajat Rohatgi, Shannon N Rhoads, Tanja Mittag, Veronica H Ryan, Yuna M Ayala |
27124 | Chemical Shifts: 1 set |
hnRNPA2 D290V low complexity domain 190-341 backbone and Cbeta chemical shifts | Disease mutation, protein interactions, and posttranslational modifications modulate hnRNPA2 liquid-liquid phase separation | Alexander E Conicella, Charlene V Chabata, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Joshua Amaya, Kathleen A Burke, Nicolas L Fawzi, Rute Silva, Veronica H Ryan |
27125 | Chemical Shifts: 1 set |
FUS low complexity domain with 12 phosphomimetic S/T to E mutations | Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity | Abigail M Janke, Alexander E Conicella, Frank Shewmaker, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Kathleen A Burke, Nicolas L Fawzi, Robert B Best, Robert N Cole, Robert O'Meally, Shannon N Rhoads, Veronica H Ryan, Wenwei Zheng, Zachary Monahan |
27123 | Chemical Shifts: 1 set |
hnRNPA2 low complexity domain 190-341 backbone and Cbeta chemical shifts | Disease mutation, protein interactions, and posttranslational modifications modulate hnRNPA2 liquid-liquid phase separation | Alexander E Conicella, Charlene V Chabata, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Joshua Amaya, Kathleen A Burke, Nicolas L Fawzi, Rute Silva, Veronica H Ryan |
27063 | Chemical Shifts: 1 set Heteronuclear NOE Values: 1 set T1 Relaxation Values: 1 set T2 Relaxation Values: 1 set |
Degenerate heptads 27-52 of human RNA polymerase II C-terminal domain (DNA-directed RNA polymerase II subunit RPB1): assignments and backbone relaxation | Lysines in RNA polymerase II C-terminal domain contribute to TAF15 fibril recruitment | Abigail M Janke, Alexander E Conicella, Dahee Seo, Jeetain Mittal, Kathleen A Burke, Nicolas L Fawzi, Vahid Rahmanian |
26831 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain engineered variant M337P | ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain | Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |
26826 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant A321G | ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain | Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |
26829 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant Q331K | ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain | Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |
26828 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain engineered variant A326P | ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain | Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |
26827 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant A321V | ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain | Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |
26830 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant M337V | ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain | Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |
26823 | Chemical Shifts: 2 sets Coupling Constants: 1 set Heteronuclear NOE Values: 2 sets T1 Relaxation Values: 2 sets T2 Relaxation Values: 2 sets |
Backbone 1H, 13C, and 15N Chemical Shift Assignments, HNHA scalar coupling, and 15N backbone relaxation data for TDP-43 C-terminal domain wild type | ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain | Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |
26672 | Chemical Shifts: 1 set |
Backbone 1H, 13C (C, CA, CB), and 15N Chemical Shift Assignments for the low complexity prion-like domain of Fused in Sarcoma (FUS 1-163) | Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II | Abigail M Janke, Christy L Rhine, Kathleen A Burke, Nicolas L Fawzi |